The immunological Bionexia^® Hb/Hp complex is based on a immunochromatographic method, in which both Hb and Hb/Hp complexes are specifi cally recognized through specifi c antibody reactions.

For Hb:
The hemoglobin contained in the stool sample reacts with specifi c monoclonal antibodies that are attached to gold particles. This complex is distributed on the membrane and reaches the test band (T) on which the anti-hemoglobin is present.

For Hb/Hp:
An antibody attaches to hemoglobin and another antibody attaches to the haptoglobin. The result is that specifi c Hb/Hp complexes are measures and there is no cross-reactivity with hemoglobin. In the case of a positive result, the molecules from the stool sample loaded with gold-marked antibodies attach to the test band (T) and are visible by means of a pink/red coloration.

In the case of a negative result, there are no hemoglobin molecules that can attach to the test band (T) as complexes and therefore, there can also be no coloration of the test band (T).